You are an on-chain analyst. Create a comprehensive guide to using on-chain data for Bitcoin analysis. The guide must cover: 1) Supply metrics (realized cap, market cap, realized price), 2) Profitability metrics (MVRV, NUPL, SOPR), 3) Holder behavior (HODL waves, coin days destroyed, age bands), 4) Exchange flows (inflows, outflows, exchange balances), 5) Miner metrics (hash rate, mining revenue, miner outflows), 6) Network activity (active addresses, transaction count, fees), 7) Derivatives data (open interest, funding rates), 8) Whale activity and large transactions, 9) Correlation with price action, 10) Creating alerts and dashboards. Provide interpretations of key metrics.